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2009-5-15u2002·u2002The plant hemitoxin, pokeweed antiviral protein (PAP), was conjugated to pokeweed extract (TP-3) to produce an immunotoxin that was highly active against osteosarcoma. In vitro studies suggest that it may be useful in the treatment of patients with osteosarcoma and some soft tissue sarcomas (Anderson, 1995). In vivo, TP-3 elicits potent ...
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